Changes in absolute lymphocyte subpopulation values of patients 9 and 4 in 2 years. Absolute numbers of CD3⁺, CD19⁺, CD56⁺ lymphocytes, and the CD3⁺CD56⁺, CD4⁺CD3⁺, or CD8⁺CD3⁺ lymphocyte subset were calculated, taking into account relative values (Figure 3) and the total lymphocyte counts for each date. Shaded area corresponds to the normal range (mean ± 2 SEM) of determinations performed simultaneously on 7 control subjects.