Figure 1.
Activities of A24 on PBMC proliferation. (A) To investigate the activity of A24 on PBMC proliferation, cells were activated with PHA/IL-2 and incubated with different concentrations of A24 (0-50 μg/mL) or control antibody 30.9 (0-50 μg/mL) for 72 hours before [3H]-thymidine incorporation. (B) Dendritic cell–induced allogenic T-cell proliferation was evaluated after 6 days of culture in the presence of A24, control antibody (30.9),9 or arsenic trioxide (Ars). Data represent means ± SD of one of 3 separate experiments.