Figure 4.
Comparative activities of A24, AZT, IFN-α, VP16, and Ars on the proliferation of tumor cells. Tumor cells from a patient with chronic ATL were incubated with or without A24 and treated with or without different chemotherapeutic agents such as AZT, IFN-α, or both AZT and IFN-α, Ars, or VP16 for 72 hours to determine the potential synergistic effect of these agents with A24. Cells were pulsed with [3H]-thymidine and harvested, before measuring the incorporation of [3H]-thymidine. Data are means ± SD of one representative experiment of 3 separate experiments.