K⁺ efflux into hypotonic NO₃^- media is insensitive to DIOA or okadaic acid in C57BL and HbCKO mice. We estimated K⁺ efflux into 250 mOsm hypotonic Cl^- (Cl), NO₃^- (NO₃), or sulfamate (SFM) media in red cells from C57BL and HbCKO mice as described in “Materials and methods.” We also measured K⁺ efflux into hypotonic NO₃^- in the presence or absence of 10 μM DIOA or 100 nM okadaic acid (OKA). The figure shows the average ± SE of 2 different experiments performed on at least 3 different mice per mouse type (For HbCKO hypotonic Cl versus hypotonic SFM, P < .02; for hypotonic Cl + OKA versus hypotonic SFM, P < .04).