Figure 9.
Cytotoxic activity of the mutated anti-CD22 immuntoxin HA22. B-CLL cells were cultured for 72 hours with indicated concentrations of BL22 or the mutated immunotoxin HA22. Apoptosis induction was determined by Annexin V staining, as described in the legend to Figure 2. Shown are means of apoptosis induction ± SEM from 7 patient samples.