Figure 1.
Figure 1. Nucleotide and deduced amino acid sequences of the VDJ-Cα,γ,ϵ variant transcripts aligned with tumor VDJ-Cμ sequences in unmutated and mutated VH gene t(11;14) mantle cell lymphoma subsets. Panel A shows the mutated subset and panel B shows the unmutated subset. The number of clones showing identical sequence are indicated in parentheses. The position of the 5′-FR3/CDR3 primer is indicated, and the position of the downstream CH primer (not shown) allowed identification of specific isotype transcripts. Tumor VH sequences have been submitted to the European Molecular Biology Laboratory (EMBL) database (AJ617568-AJ617575).

Nucleotide and deduced amino acid sequences of the VDJ-Cα,γ,ϵ variant transcripts aligned with tumor VDJ-Cμ sequences in unmutated and mutated VH gene t(11;14) mantle cell lymphoma subsets. Panel A shows the mutated subset and panel B shows the unmutated subset. The number of clones showing identical sequence are indicated in parentheses. The position of the 5′-FR3/CDR3 primer is indicated, and the position of the downstream CH primer (not shown) allowed identification of specific isotype transcripts. Tumor VH sequences have been submitted to the European Molecular Biology Laboratory (EMBL) database (AJ617568-AJ617575).

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