Figure 1.
![Figure 1. Cytokine gene expression profiles in adult chronic ITP patients. Expression (mean ± SEM) of the cytokines studied at the mRNA level in control subjects, patients in active disease phase (PLT count < 100 × 109/L [< 100 000/mm3]), and patients in hematologic remission by peripheral blood mononuclear cells ex vivo and after in vitro stimulation with PMA and ionomycin (P/I). Asterisks denote significance using unpaired 2-tail t test (*P < .05; **P < .01). Comparisons among subject groups (controls, patients with active disease, and patients in remission) were made under the same experimental conditions (ex vivo PBMCs or stimulated PBMCs) for each cytokine separately.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/103/7/10.1182_blood-2003-07-2268/6/zh80070459070001.jpeg?Expires=1735818180&Signature=gii9EkkruiGOctpdmCsw39-QLLnbmIWuA3D6Z~e2ChJtSpXcrH0y3zQ-iBLc3xL65aAPxhm1m1ayqXhKYFiVFpzS5yq95ZbJE-LVd468F-d-JWBAwQFcyaLkvAgid7VKTY7Xl47nBx-G~wDIkoRHzcC~k32NA-gV5iYjqACccZlp4~LtMF25tZlMetaUyrPv-PLbQPtoqKC~MQapf2iwrpR2sKTRDwjkGE4WNfh5bxkhZNAd8KH3tF2mJsO0pkN00qmjXClJ3UbyyC7zmBXu9751z1nyBt~yKEKXQ-Xc1Oa-RfaJPuQoSdXDiuz-sT9zWpC5Yk4-AK7ppypzFRMthA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Cytokine gene expression profiles in adult chronic ITP patients. Expression (mean ± SEM) of the cytokines studied at the mRNA level in control subjects, patients in active disease phase (PLT count < 100 × 109/L [< 100 000/mm3]), and patients in hematologic remission by peripheral blood mononuclear cells ex vivo and after in vitro stimulation with PMA and ionomycin (P/I). Asterisks denote significance using unpaired 2-tail t test (*P < .05; **P < .01). Comparisons among subject groups (controls, patients with active disease, and patients in remission) were made under the same experimental conditions (ex vivo PBMCs or stimulated PBMCs) for each cytokine separately.
