Figure 2.
Effect of hepcidin on iron absorption in mice. Mice were injected daily for 3 days with 0.15 M NaCl (controls; ▪) or hepcidin (10 μg [] or 100 μg [□]) dissolved in 0.15 M NaCl. Tied-off segments of duodenum were incubated with 250 μM 59FeNTA2 for 10 minutes. Data show radioiron retained by the duodenal tissue (MR), radioiron transferred to the carcass (MT), and total uptake of radioiron by duodenum (TMU). *P < .05, **P < .01.