TEL-AML1 confers an advantage on reconstitution by HPCs in vivo. Sublethally irradiated mice were reconstituted with uninfected HPCs (UN; triangles) or HPCs transduced with MSCV-EGFP (M-G; squares) or MSCV-T/A (M-T/A; circles) (n = 6 for each group). Flow cytometry was performed on peripheral blood 3 weeks after transplantation (left panel) and on splenocytes (middle panel) and bone marrow cells (right panel) from the same mice 6 weeks after transplantation. Ly5.2⁺Ly5.1^– cells were gated and EGFP expression was analyzed. Plots show the percentage of EGFP^–Ly5.2⁺ (open symbols) and EGFP⁺Ly5.2⁺ (filled symbols) donor-derived cells in the mice that received transplantations. Each symbol represents data from an individual mouse, and bars represent the means within each group.