Figure 3.
Quantitative assessment of atherosclerosis. At 23 weeks after pI:pC induction, the extent of atherosclerosis in LRPflox/floxLDLR–/–APOE–/– (○) or MX1Cre+LRPflox/floxLDLR–/–APOE–/– (•) mice was quantified at the level of the aortic root. Each data point represents the mean lesion area per mouse. Significant differences are indicated; P < .05.