Hematologic parameters of naive or P chabaudi AS–infected mice, either untreated or treated with 10 units of recombinant murine EPO (rmEPO) per day for 3 days. Parasitemia and hematologic parameters were determined after the completion of EPO treatment. (A) Parasitemia; (B) total RBCs; (C) total reticulocytes. Data are means ± SEM for 5 mice per group. N indicates untreated naive controls; N+EPO, naive mice treated with EPO; I, untreated infected controls; I+EPO, infected mice treated with EPO. Lowercase letters above each bar represent the result of statistical comparison. When 2 bars are labeled with different letters, it indicates that these 2 sets of data are statistically different (P < .05). Similar results were obtained in 4 independent experiments. N/A indicates not applicable.