Figure 3.
In vitro proliferative effect of MLL-GPHN and its mutants. (A) Forced expression of MLL-GPHN full and ex14 immortalize murine hematopoietic progenitors. The bars represent number of colonies generated per 104 cells in first, second, and third rounds of plating in methylcellulose. The error bars represent the mean ± SD of triplicate samples from a representative experiment. (B) Detection of MLL fusion protein expression in Phoenix cells by Western blot analysis.
