Histologic and phenotypic analysis of human thymus grafts from NOD/SCID-Tg mice that received human Thy/Liv implants. Thy/Liv grafts were removed at week 20 after human tissue implantation from the recipients of porcine BM transplants plus human Thy/Liv grafts (n = 13) or the NOD/SCD-Tg mice that received human Thy/Liv tissues alone (n = 7). (A-C) Data shown are results of a representative graft. (A) Macroscopic appearance. (B) Histology (hematoxylin and eosin; original magnifications × 10 [left panel] and × 40 [right panel]); C indicates cortex; M, medulla; H, Hassall corpuscles. (C) Phenotypic analysis by FCM. (D) Percentages (means ± SD) of human thymocytes expressing various surface markers in the Thy/Liv grafts from NOD/SCID-Tg mice that received porcine BM transplants plus human Thy/Liv (□; n = 13) or human Thy/Liv tissues alone (▪, n = 7).