Contribution of VEGFRs to P-selectin translocation. Prior to stimulation with the indicated VEGF analogs (10^–9 M; 7.5 minutes), HUVECs were pretreated for 15 minutes with (A) a selective VEGFR-2 inhibitor (SU1498; 5 × 10^–6 M) or (B) either a GST fusion protein containing either exon 7 of human VEGF-A₁₆₅ (GST-Ex7) or GST. Data are means ± SEM of at least 6 experiments, *P ≤ .05 and ***P ≤ .001 as compared to DPBS, ††P ≤ .01 and †††P ≤ .001 as compared to corresponding VEGF analogs.