Figure 1.
Characterization of CCR7–/CD62Llow CD4+ T-cell populations. (A) Representative dot plot showing CCR7 and CD62L expression on a gated population of CD4+ T cells in a healthy donor and a patient with cGVHD. (B) Pooled data showing the percentage of CCR7–/CD62Llow total CD4+ cells in healthy donors (▪, n = 36), stem cell transplantation patients without cGVHD (▴, n = 20), and stem cell transplantation patients with cGVHD (•, n = 25). (C) Pooled data showing the percentage of CCR7–/CD62Llowmemory (CD45RO+) CD4+ cells in healthy donors (▪, n = 20), stem cell transplantation patients without cGVHD (▴, n = 11), and stem cell transplantation patients with cGVHD (•, n = 18). Horizontal lines indicate the mean values.