Figure 2.
Two patterns of engraftment of MDS cells in NOD/SCID-β2m-/- (and NOD/SCID-β2m-/--3/GM/SF) mice. Values shown are the mean ± SEM of total human hematopoietic (CD45/71+) cells in mice assessed individually at at least 2 time points (2 to 6 mice/patient sample for patients 3, 5, 7, and 10; 1 mouse/patient for patients 1, 2, 8, 9, and 11). Data are for NOD/SCID-β2m-/--3/GM/SF mice except for patients 2 and 5, which are from NOD/SCID-β2m-/- recipients. Data were generated as described in Figure 1.