Altered patterns of differentiation seen in NOD/SCID-β2m^-/- mice engrafted with human MDS cells. Representative FACS profiles of cells aspirated from the BM of a mouse that received a transplant 3 weeks previously with cells from patient 3 (A) and from the BM of a mouse that received a transplant 7 weeks previously with cells from patient 9 (B), in both instances showing a predominance of human granulopoietic (CD15/66b⁺) cells.