Figure 1.
Cellular distribution of 440c antigen within murine splenocytes. (A) In total splenocytes, mAb 440c recognizes subsets of CD11c+ and Ly-6C+ cells, but not CD11b+, CD3+, CD19+, or DX5+ cells. (B) Within CD11c-enriched splenocytes, mAb 440c recognizes a Ly-6C+/B220+/CD8αhi/lo/CD11b- subpopulation. Plots represent gated CD11c+ cells. (C) mAb 440c recognizes only CD11c+/Ly-6C+ cells within splenocytes derived from mice that have been injected intraperitoneally with MCMV.