FGF-2-induced HUVEC proliferation. FGF-2 (10 ng/mL)-induced HUVEC proliferation on collagen IV (50 μg/mL) was evaluated. Cells were treated for 24 hours at 37°C with increasing RGDS concentrations. RGDS significantly reduced endothelial cell proliferation (^*P < .05 at 500 μg/mL RGDS). Data are expressed as mean ± SE of 3 experiments carried out in duplicate.