Figure 2.
Representative TCR Vβ CDR3 size spectratype obtained from the liver of a patient with HAA showing many highly skewed spectratypes. Vβ13 and Vβ23 show a normal or Gaussian bell-shaped distribution; Vβ7 and Vβ24 demonstrate a skewed spectratype profile with a single dominant peak; Vβ2 and Vβ9 illustrate a skewed spectratype profile with double peaks; Vβ16 shows multiple peaks but with non-Gaussian distribution and skewed spectratype. The complexity score for each spectratype is given in the upper right corner. The overall complexity score was calculated as 70. The abscissa shows CDR3 length (amino acids), and the ordinate shows fluorescence intensity.