Comparison of the T-cell repertoire by different methods in 10 healthy donors and 3 HAA patients before and after immunosupression therapy. Data (mean ± SD) illustrate a return toward a normal T-cell repertoire after successful treatment. The percentage of absent and skewed spectratypes in peripheral blood lymphocytes were first evaluated by observation, then the percentage of skewings of V_β spectratypes were evaluated by RI, and the complexity scores were calculated.