Abbreviated pedigree of Carolinas kinship A with juvenile hemochromatosis (JH). JH patients II-5 and II-6 were described in a previous report.⁹  Arrows designate JH index cases in respective sibships. Ages (in years) are those at time of manuscript preparation (or death); clinical and laboratory findings reflect observations at the time of diagnosis of JH patients or evaluation of corresponding family members. Tf sat indicates serum transferrin saturation; Ftn, serum ferritin concentration. Determined alleles of HFE and HJV are displayed without parentheses, deduced genotypes within parentheses. The arrows designate the subjects used for DNA analysis.