The role of PI3Kδ in supporting neutrophil-endothelial cell interactions in vivo. (A) Representative intravital fluorescence micrograph depicting accumulation of GFP-expressing cells on inflamed venules in WT animals pretreated with either vehicle alone (i) or IC87114 (ii), or in GFP^+/-/p110δ^-/- mice (iii). (B) Percentage of cells attaching to and rolling on TNFα-stimulated microvessels per minute in the absence or presence of inhibitor. ^*P < .01 versus control. A total of 15 venules were analyzed in 5 animals for each control or experimental group. Data represent the mean ± SD.