Figure 1.
Antibody responses to intradermal DNA OVA immunization is higher in C57BL/6 than bm1 mice. Six-week-old C57BL/6 and bm1 mice were injected with DNA plasmid encoding secreted OVA. Anti-OVA IgG antibodies were measured by ELISA at 4 weeks. Antibody levels were higher in C57BL/6 than in bm1 mice following intramuscular (n = 5; P = .09) and (*) intradermal immunization (n = 8; P = .001), although significance was only shown in the latter. Mean and standard deviation are shown. Preimmune antibody in both these strains is always undetectable against OVA.