Figure 2.
Binding of anti-α2 I-domain mAbs to resting and convulxin-stimulated platelets. Flow cytometric analysis on platelets (PRP, 5 × 105 platelets/μL) with 20 μg/mL mAb MOPC-21 (negative control), Gi9 (positive control), 1D12, or IAC-1. Platelets were either nonactivated (filled histogram) or convulxin stimulated (50 ng/mL; open histogram). Overlays are representatives of at least 3 experiments.