Figure 6.
Convulxin dose dependently raises several platelet activation markers. Flow cytometric detection of the binding of FITC-labeled IAC-1 (70 μg/mL; •), PAC-1 (1:10 vol/vol; ○), Gi9 (20 μg/mL; ⋄), or collagen (100 μg/mL; ▪) to platelets in PRP; stimulation was with indicated concentrations of convulxin. Data are represented as the ratio of MF of stimulated versus unstimulated platelets and are representative of 3 independent experiments.