Figure 1.
Family pedigree for patient 1 (fXI-Gly400Val). The bold arrow indicates patient no. 1, while the asterisk indicates the original proband from the study by Litz et al.16 Symbols filled in black represent family members with bleeding symptoms. Plasma fXI activity levels are indicated below each symbol.16 A diagonal slash indicates that the person is deceased. The figure is modified from Litz et al16 and reprinted by permission of Wiley-Liss Inc, a subsidiary of John Wiley & Sons Inc.