Effect of PTX3 on FGF2-induced neovascularization. (A) Chick embryo CAMs were implanted with gelatin sponges adsorbed with vehicle, FGF2 (0.028 nmoles/embryo), PTX3 (0.11 nmoles/embryo), or both. At day 12, the angiogenic response in each egg was graded. Bars represent the mean ± SEM of 10 to 15 embryos per group. (B) Representative CAMs implanted with gelatin sponges adsorbed with FGF2 alone (i) or FGF2 plus PTX3 (ii). Original magnification, × 5.