Endothelial TF expression in pulmonary veins. TF expression is scored as percent of pulmonary veins positive for TF (mean ± SD). Normal mice (Nor), HbA-expressing control mice (HbA-BERK), and mild sickle mice (NY1DD) have the same low-TF expression. TF expression by the moderately severe S+S-Antilles mouse is higher, and that of the severe BERK mouse is the highest. Statistical significance: P = ns (not significant) for NY1DD (n = 10) versus Nor (n = 9); P = .004 for S+S-Antilles (n = 4) versus Nor (n = 9); and P < .001 for BERK (n = 5) versus HbA-BERK (n = 5).