Lovastatin inhibits TF expression. Data are expressed as for Figure 3. The elevated TF expression of the posthypoxic NY1DD mouse is inhibited by a 5-day pretreatment with lovastatin. The elevated TF expression of the severe hBERK1 mouse at ambient air is inhibited by a 2-week pretreatment with lovastatin (n = 8). Statistical significance: P < .001 for posthypoxic NY1DD animals with (n = 6) versus without (n = 9) lovastatin; P = .002 for hBERK1 animals with (n = 8) versus without (n = 9) lovastatin.