Figure 5.
Effect of exogenous IL-12 on TH1-polarizing activity of BCP-ALL cells. BCP-ALL cells or CD40L-activated BCP-ALL cells were cocultured with purified cord blood T lymphocytes in the presence or absence of 20 ng/mL IL-12. After 6 days, IFN-γ and IL-4 production by T cells was assessed by intracellular staining. Data are expressed as the percentage of cytokine-producing cells.