Figure 2.
In vivo tumor formation. (A-D) Kinetics of tumor formation. L3055 and HK cells were inoculated in nude mice for tumor formation. Paraffin sections of tumor tissue were stained with Hematoxylin and Eosin on day 3 (A), 7 (B), 10 (C), and 14 (D) after the inoculation. Original magnification, × 200. (E) Cell-surface phenotype indicates that the tumor cells are derived from L3055 cells. HK, L3055, and tumor cells (60 days after the inoculation) were stained with murine IgG1 as a negative control (white histograms); mAbs 8D6, 4G10, 3C8, CD44, CD20, and CD38 (red histograms) are as indicated. Flow cytometric analysis was carried out on a FACSCalibur by using CELLQuest Pro software.
