Figure 3.
Effect of oral L1 administration on serum ferritin (SF) and red bloodcell membrane (RBCM) iron levels. Grouped profiles. The figure depicts results obtained either monthly or bimonthly with 17 patients showing mean ± SEM values for serum ferritin SF (in nanograms per milliliter, • and broken line) and RBCM (nanomoles per milligram of protein, □ and solid line). The lines represent the nonlinear least square fit based on a single exponential decay function as described in the legend of Figure 2; for RBCM iron, A1 = 37.2 ± 2.6, y0 = 8.0 ± 1.5, and t1 = 5.7 ± 0.8 (r = 0.94); and for SF, A1 = 3407 ± 868, y0 = 550 ± 250, and t1 = 8 ± 0.8 (r = 0.90). The linear correlation between SF and RBCM iron given in the inset yielded a slope of 0.011 ± 0.001, intercept 0.9 ± 1.5. and r = 0.92.