Figure 4.
Myeloid developmental abnormalities in XID mice. (A) Total white blood cell (WBC) numbers in the blood of WT and XID mice (mean ± SE). (B) Differential WBC frequencies (N: PMNs; L: lymphocytes; M: monocytes; E: eosinophils) in the blood of WT and XID mice (mean ± SE). (C) Total bone marrow cell yields per femur from WT and XID mice (mean ± SE). (D) Granulocytic lineage (Gr-1+) cell numbers in bone marrow from WT and XID mice (mean ± SE). (E) CD54 intensity in Gr-1+CD11blo (thin line) and Gr-1+CD11bhi (thick line) cells from WT bone marrow. (F) Early granulocytic lineage (Gr-1+CD11blo) cell numbers in bone marrow from WT and XID mice (mean ± SE). (G) CD54 intensity in Gr-1+CD11bhi cells from WT (thin line) and XID (thick line) WT bone marrow. (H) Late granulocytic lineage (Gr-1+CD11bhi) cell numbers in the CD54hi and CD54lo subpopulations from bone marrow of WT and XID mice (mean ± SE). (I) Monocytic lineage (CD11b+Gr-1-) cell numbers in bone marrow from WT and XID mice (mean ± SE). (J) Myeloid colony-forming cell numbers in bone marrow from WT and XID mice (mean ± SE).