NO adducts in RBCs isolated from control and LPS rats. (A) RBC nitrate and nitrite concentrations at 5 and 10 hours following LPS administration compared with control. Data represent mean ± SEM (n = 3). (B) SNO concentrations in LPS RBCs relative to control RBCs. Data represent mean ± SEM (n = 3). (C) Representative EPR spectra of RBCs from saline-injected rats (gray line) versus RBCs isolated from LPS-treated rats (black line). *P ≤ .05 versus control.