Immunohistology of heart and kidney from saline- or LPS/l-NAME–treated control and Tg mice. All sections were stained with an antifibrinogen antibody that also detects fibrin (green) and with the nuclear stain DAPI (blue) (original magnification × 100). White arrows indicate vessels with intraluminal clot. No staining was detected in organs from saline-treated Hir-Tg or TFPI-Tg mice (data not shown).