The allelic ratio ofAML1assessed by SNP analysis. (A-B) The representative electropherograms show the sizes and levels of allele 1 (A1) and allele 2 (A2) after restriction digestion of SNP1 in panel A and of SNP2 in panel B. Top row shows healthy controls; middle row, patients with allelic balance; and bottom row, patients with allelic ratios significantly different from the controls, suggesting allelic imbalance. (C-D) The allelic ratio is depicted as dots of the 10 patients heterozygous for SNP1 (C), and of the 9 patients heterozygous for SNP2 (D). The mean values from 3 separate experiments are given with standard deviations (thin vertical lines). Two patients showed allelic imbalance of SNP1 (cases 50 and 72), and 2 patients disclosed allelic imbalance of SNP2 (cases 62 and 97).