Constitutively active RBP-Jκ inhibits endothelial migration. HMEC migration was assayed by a Transwell filter assay in response to basal medium, FGF-2 (15 ng/mL), or VEGF (30 ng/mL). Cells migrating to the underside of the filter were quantitated and graphed as means + SE for the average of 3 experiments, each done in duplicate. ^*P < .05 compared with the vector control.