Time to onset of grade 2 bleeding. (A) Time to onset of grade 2 bleeding in ITT population (n = 645). Median time to onset of grade 2 bleeding was 8 days, log rank P = .78. (B) Time to onset of grade 2 bleeding in patients with no (grade 0) bleeding at baseline (n = 541). Median time to onset of bleeding more than 31 days, log-rank test P = .91.