Influence of humoral immunity on potent viremia control. Patients were stratified according to their ability to potently suppress viremia upon STI to levels below 5000 RNA copies per milliliter of plasma for at least 8 weeks (n = 46). White and gray circles demarcate controlling and noncontrolling patients, respectively, and horizontal bars indicate mean values. All significant observations were significant on the individual level and also after Bonferroni correction. (A) Viral loads before ART and after STI are depicted. Anti-gp120 (B) and anti-p24 (C) titers at baseline (weeks 0 to 2) and maximum increases in titers reached during the trial are shown.Antibody reactivities and viral loads of the individual groups were compared using the unpaired t test.