Thrombocytopenic purpura induced by LDV infection in nude mice. (A) Global clinical picture and skin detail of BALB/c nu/nu mice 1 day after administration of IgG from polyclonal anti-mouse platelet rabbit serum (anti-plt Ab) (3 μg; iii-iv) or control rabbit IgG (i-ii) and of LDV (ii, iv) or saline (i, iii). Photographs were taken with a Nikon Coolpix 4500 (Nikon, Tokyo, Japan). (B) IgG (3 μg) from polyclonal anti-mouse platelet rabbit serum or control rabbit IgG was injected into groups of 4 BALB/c nu/nu mice with LDV infection or administration of saline. Platelets were counted 2 days later (○ represents each individual datum; •, means ± SEM). Panels A and B represent independent experiments.