Up-regulation of the hTERT expression in in vivo ATLL patient samples. Real-time PCR measure of hTERT mRNA expression in 2 donors negative for HTLV-I, 2 asymptomatic carriers (AS), and 4 ATLL patients was performed as described in “Materials and methods.” The expression level in nonactivated cultured PBMCs (shown in Figure 1A) was defined as 1.0. Experimental variations are indicated by error bars.