Figure 5.
F(ab′)2 fragments of APS IgG increase monocyte TF activity. Normal monocytes were incubated for 6 hours with APS or normal IgG (250 μg/mL, ▪) or equimolar concentrations of the corresponding F(ab′)2 fragments (▨), and β2GPI (100 μg/mL), washed, and assayed for TF activity. Controls were media alone (□) and LPS (500 ng/mL, ▩). Data shown are the mean ± SEM of triplicate determinations.