Figure 6.
Dilazep inhibits APS IgG-induced monocyte TF activity. (A) Normal monocytes were stimulated with LPS (500 ng/mL), APS IgG (250 μg/mL), or RP-1 (50 μ/mL) in the presence or absence of dilazep (100 μg/mL), washed, and assayed for TF activity. Data shown are the mean ± SEM of duplicate determinations. (B) Normal monocytes were stimulated with LPS or APS IgG in the presence of varying concentrations of dilazep, washed, and assayed for TF activity. Data shown are the mean ± SEM of duplicate determinations. Assays of APS IgG and RP-1 were performed in the presence of β2GPI (100 μg/mL).