Figure 3.
Flt3L expands class II+/CD11c+ cells following BMT. Thymus-bearing (Thy-B) and TXY C57BL/6 received 1 × 107 B6/CD45.1 T cell-depleted BM cells and 1 × 106 B6/Thy1.1 LN cells following 1000 cGy as described in “Materials and methods.” Nonirradiated mice were included as controls. Flt3L (5 μg per day) was administered from day 1 to 28. On day 29, class II+/CD11c+ splenocytes were enumerated by flow cytometry; n = 8 animals per group. Data are representative of 3 independent experiments. Graph shows median values with bars representing standard error.