Figure 7.
Effect of hirudin on survival of syngeneic mice injected subcutaneously with 1 × 105 4T1 breast carcinoma cells. Animals were treated with either PBS (control group) or hirudin (10 mg/kg) 5 minutes before and 10 days thereafter plus every other day for 10 days, and observed. (A) Refers to number of dead mice in control and hirudin-treated groups. □ indicates number of mice at start of experiment; ▪, number of dead mice by day 30. (B) Kinetic analysis of animal survival.
