Figure 4.
Expression of CD34 and CD10 or CD19 on ALL progenitor cells. ALL cells from 19 patients were sorted for expression of CD34 and CD10 (A), and cells from 16 patients were sorted for coexpression of CD34 and CD19 (B). The proliferative capacity of the sorted subfractions and unsorted controls was evaluated in SC. Absolute cell counts, derived from each sorted population, and unsorted controls were determined by flow cytometry at weeks 1, 3, 5, and 6. These values were then used to calculate the proportion of the total viable cells represented by each sorted population. The proportion of the total cells derived from the each sorted subfraction is presented as the mean ± SE; n indicates number of patient samples evaluated at each time point.