Dermal IFP and cellular density in PDGF-D–overexpressing mice. (A) The IFP measured from the dermis was between –1.1 and –2.1 mm Hg (± 0.065) in wild-type mice and between –1.0 and –1.5 (± 0.136) in transgenic mice. This difference was statistically significant (n = 7 in both groups; ^*P = .0175). (B-C; data not shown) The staining of nuclei was used to calculate cell density in the skin (original magnification, × 200). Careful counting indicated no difference in the cell densities between the transgenic and wild-type mice.