Figure 3.
Wound healing and macrophage numbers in K14-PDGF-D and control mice. (A) Kinetics of wound closure in the transgenic mice and wild-type littermates (mean ± SD). (B) Total number of macrophages in the wound area in transgenic mice and their littermates at various days of the healing process (*P = .0227; **P = .0364; day 4, n = 5; days 5, 7, n = 4; day 10, n = 3). Values are expressed as mean ± SD. (C-D) Typical wounds from day 7. Boxed areas show examples of the areas from which the total cell counts and macrophage counts were obtained (1 box = 4 × 104 μm2) (original magnification, × 40).