Tissue stains and levels of serum sCD30 and sIL-2R. (A) Immunohistochemical staining of tumor tissue for CD30, CD25, ALK1, and hematoxylin and eosin stain of tissue. Images were viewed under an Olympus BX41 microscope equipped with UPlan F1 40 ×/0.75 objective lenses and an Olympus DP12 digital camera (Olympus, Melville, NY). Images were imported with an Olympus Camedia USB Smartmedia card reader into Adobe Photoshop 7.0 (Adobe, San Jose, CA) for processing. (B) Correlation of serum sCD30 and sIL-2R levels in patients with ALCL. Correlation coefficient r = 0.97. (C) Serum sIL-2R levels during therapy with EPOCH infusional chemotherapy. The elevated levels seen before therapy normalized within one cycle of treatment.